Early on a bitter cold Minnesota morning, three robbers burst into a hospital pharmacy, duct-tape the pharmacy workers, and clean the place out. Things then swiftly go bad when one of the workers dies. In a hurry to rush out the robbers, for a split-second, come face-to-face with a woman in the garage: Weather Karkinnen, surgeon and wife of investigator Lucas Davenport. Gnawing it over later, they come to one conclusion: find out who she is, and eliminate the only possible witness.